Why Karyopharm Therapeutics is Most Loved

Karyopharm Therapeutics is a global leader in oncology innovation; its pioneering SINE (Selective Inhibition of Nuclear Export) technology targets cancer cells in a novel way for blood cancers and solid tumors. Headquartered in Newton, MA, with its first FDA-approved product now available across the U.S., Europe, and Asia and a pipeline extending into rare diseases.

Positive Vision: A bold path to defeat cancer, with every employee playing a role in delivering life-changing therapies.
Values: ICARE: Innovation, Courage, Alignment, Resilience, Energy, embedded in talent management and the ICARE Awards.
CEO Strengths: Richard Paulson champions innovation and resiliency, sets clear goals, and genuinely cares about people while scaling a commercial-stage biotech.
Respect: Open forums and programs promoting transparency, integrity, and diversity of thought; ERGs and Inclusion & Wellness.
Loved Culture: A cross-functional, silo-breaking environment where every contribution is valued.
Benefits: Competitive comp, an industry-leading flexible/remote model with monthly Core-Weeks, KaryoFlex Fridays, a $1,200 wellness stipend, Headspace, and HRA/HSA medical plans. Commitments: half-day Fridays year-round, pet insurance, volunteer time off, wellness & development stipends, tuition reimbursement, 401(k), mentorship programs.

Best Practice Institute

Best Practice Institute is the research organization behind Most Loved Workplace® certification, the SPARK Model, the Love of Workplace Index®, and The Workplace Report.

The Workplace Report

The Workplace Report is BPI's original workplace culture research and editorial briefing series for CEOs, CHROs, people leaders, talent leaders, and employer-brand teams. It turns BPI's 25 years of research, Most Loved Workplace® certification data, SPARK findings, and current workforce signals into practical analysis leaders can use.

The report format includes executive summaries, research-backed articles, company examples, methodology notes, and practical implications for retention, hiring, culture, leadership, and employee experience. New research and analysis is published on an ongoing editorial cadence at /workplace-report.